Glowing, resilient skin remains a top priority for aesthetic enthusiasts seeking effective skin rejuvenation. Modern aesthetic medicine has moved beyond simple surface moisturizers, shifting focus toward deep cellular repair. If you struggle with persistent fine lines, enlarged pores, or stubborn textural irregularities, regenerative skin boosters offer a science-backed solution that heals your skin from the inside out.
Stepping into an aesthetic clinic for a Rejuran skin booster treatment marks the beginning of an exciting skin transformation. Formulated with Polynucleotides (PN) derived from wild salmon DNA, this injectable treatment stimulates collagen production, improves skin elasticity, and accelerates cellular repair. Understanding the step-by-step process of your initial session ensures you walk into your appointment feeling relaxed, informed, and completely prepared.
Preparation and Prep Work: Numbing and Pre-Treatment Care
Your treatment journey begins with a thorough cleansing of your face to remove all makeup, dirt, and excess oil. Once your skin is pristine, a therapist applies a medical-grade topical numbing cream across the entire treatment area.
- Numbing Duration – The topical anaesthetic sits on your skin for 20 to 30 minutes, ensuring maximum comfort during the procedure.
- Skin Assessment – Your doctor reviews your target areas, identifying regions that require extra repair, such as acne scarring, fine lines, or sun-damaged skin.
- Sanitisation – After wiping off the numbing cream, your practitioner sanitises your skin with an antiseptic solution to maintain a sterile environment.
- Comfort Checks – Your clinician verifies that the numbing effect has fully kicked in before beginning the micro-injection process.
The Micro-Injection Process: What the Treatment Feels Like
Once the numbing cream takes full effect, your doctor begins administering the Rejuran skin booster using precise micro-injections across your face. The doctor deposits tiny droplets of the bio-regenerative gel into the upper dermis layer, creating small, visible bumps on the skin surface.
While the numbing cream minimises sharp discomfort, you may feel mild pressure or a slight stinging sensation in delicate areas like the under-eye region or forehead. The entire injection phase takes only 15 to 20 minutes to complete. Many patients undergoing comprehensive facial rejuvenation choose to combine this cellular repair treatment with targeted acne scar treatment in Singapore to smooth uneven skin texture and boost overall skin healing.
Post-Treatment Appearance: The Immediate Aftermath and Recovery
Immediately after your session, your face will display small, raised bumps resembling tiny mosquito bites at each injection site. These bumps are entirely normal; they hold the concentrated polynucleotide gel as your skin gradually absorbs the active healing ingredients over the next 24 to 48 hours.
You may also experience mild redness, slight swelling, or minor pinpoint bruising around sensitive areas. These temporary side effects usually subside within two to three days. Your clinic provides a soothing post-treatment mask or cooling cream to calm your skin immediately after the micro-injections. You can return to your routine activities right away, provided you follow simple post-care guidelines like avoiding harsh sunlight, intense workouts, and heavy makeup for the first 24 hours.
Spotting the Results: When Your Skin Begins to Transform
Unlike hyaluronic acid dermal fillers that add immediate volume, biological skin boosters work progressively at a cellular level. The salmon-derived polynucleotides stimulate fibroblasts, encouraging your body to produce fresh collagen and restore damaged dermal structures.
Within one to two weeks, you will notice improved hydration levels, smoother skin texture, and reduced oil production. Over the following month, your skin becomes visibly firmer, clearer, and more resilient. Patients seeking effective acne scar treatment in Singapore will observe gradual softening of shallow indents and refined pore sizes as fresh collagen rebuilds the skin matrix from within. Doctors typically recommend an initial series of three to four monthly sessions to achieve optimal, long-lasting rejuvenation.
Frequently Asked Questions
Is the Rejuran treatment painful?
Most patients tolerate the treatment exceptionally well. The application of a high-strength topical numbing cream prior to injection ensures minimal discomfort, leaving you with only mild prickling sensations.
How long do the results of Rejuran skin boosters last?
After completing the recommended initial series of three to four sessions, the regenerative results typically last between 6 to 12 months. Periodic maintenance sessions every six months help sustain your glowing results.
Can I combine Rejuran with other aesthetic treatments?
Yes. Doctors often pair polynucleotide injections with laser therapies or micro-needling treatments to enhance overall collagen production and deliver superior skin texture improvements.
Embrace Natural Skin Regeneration
Experiencing your first skin booster session opens the door to healthier, stronger, and more luminous skin. By understanding what happens during preparation, injection, and recovery, you can navigate your treatment path with complete confidence. Investing in biological cellular repair restores your natural glow and strengthens your skin barrier for long-term health.
Whether you want to revitalise your complexion with a Rejuran skin booster or seek specialised acne scar treatment in Singapore, modern aesthetic care delivers visible, beautiful results. Contact Shens Clinic today to book your consultation and start your journey toward radiant skin!

